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Syphilis Is Back — Here’s What the Screening Test Looks Like

Syphilis rates have risen sharply over the past decade, reversing a long trend of decline — one more reason routine screening matters more than ever.

Our Syphilis Screen uses the RPR test, a long-established method that looks for a substance the body produces in response to infection. If the result is reactive, the lab automatically runs a confirming test.

Why syphilis is easy to miss

Early syphilis can cause a single painless sore that many people never notice or mistake for something else entirely — and the infection can then go quiet for a long stretch before causing more serious problems later. Testing, rather than waiting for symptoms, is the reliable way to catch it.

What to expect

No fasting needed. As with other STI tests, results appear only in your private portal.

Ready to order? The Syphilis Screen (RPR) is $34 at SelectATest, with results in your own secure online portal.

This post is for general information and does not replace advice from your own doctor. Tests are ordered by an independent licensed physician, and results are not a diagnosis. If you are having a medical emergency, call 911.